Repositorio UNINCOL: Items where Division is "Universidad Internacional do Cuanza > Research > Articles and books" and Year is [pin missing: value2]

Adherence to the Mediterranean diet, inflammatory biomarkers and cognitive status in older Italian adults.

Advancements in Dentistry with Artificial Intelligence: Current Clinical Applications and Future Perspectives.

Advancing fake news combating using machine learning: a hybrid model approach.

Analysis and Implementation of Human Mobility Behavior Using Similarity Analysis Based on Co-Occurrence Matrix.

An Analytical Framework for Innovation Determinants and Their Impact on Business Performance.

Antifragile and Resilient Geographical Information System Service Delivery in Fog Computing.

Chronic obstructive pulmonary disease (COPD) is a severe and chronic ailment that is currently ranked as the third most common cause of mortality across the globe. COPD patients often experience debilitating symptoms such as chronic coughing, shortness of breath, and fatigue. Sadly, the disease frequently goes undiagnosed until it is too late, leaving patients without the care they desperately need. So, COPD detection at an early stage is crucial to prevent further damage to the lungs and improve quality of life. Traditional COPD detection methods often rely on physical examinations and tests such as spirometry, chest radiography, blood gas tests, and genetic tests. However, these methods may not always be accurate or accessible. One of the key vital signs for detecting COPD is the patient’s respiration rate. However, it is crucial to consider a patient’s medical and demographic characteristics simultaneously for better detection results. To address this issue, this study aims to detect COPD patients using artificial intelligence techniques. To achieve this goal, a novel framework is proposed that utilizes ultra-wideband (UWB) radar-based temporal and spectral features to build machine learning and deep learning models. This new set of temporal and spectral features is extracted from respiration data collected non-invasively from 1.5 m distance using UWB radar. Different machine learning and deep learning models are trained and tested on the collected dataset. The findings are promising, with a high accuracy score of 100% for COPD detection. This means that the proposed framework could potentially save lives by identifying COPD patients at an early stage. The k-fold cross-validation technique and performance comparison with the state-of-the-art studies are applied to validate its performance, ensuring that the results are robust and reliable. The high accuracy score achieved in the study implies that the proposed framework has the potential for the efficient detection of COPD at an early stage.

An Approach to Detect Chronic Obstructive Pulmonary Disease Using UWB Radar-Based Temporal and Spectral Features.

An Artificial Neural Network-Based Approach for Real-Time Hybrid Wind–Solar Resource Assessment and Power Estimation.

Association between blood cortisol levels and numerical rating scale in prehospital pain assessment.

With the growing academic pressure and competitive educational environment, students often face mental stress, which can affect their academic performance and mental health. Its accurate and timely detection and prevention is important. Traditionally, mental stress has been reported by self-assessment, which is highly subjective and can be erroneous. With advances in neuroscience, electroencephalogram (EEG) signals have been used to study brain states more objectively. EEG-based features, including time-domain, frequency-domain, and various types of connectivity features, have been used to effectively classify stress signals. However, these individual features are only able to present one aspect of the brain under stress. Several studies have combined a distinct set of features extracted from EEG signals, including time and frequency domain features, with other peripheral signals. Stress is a complex mechanism which leads to alternation in brain dynamics, its connectivity patterns and information flow. This study proposed a feature-fusion model that can effectively combine spatial features, i.e. Microstates (MS), connectivity features like Transfer Entropy (TE) and Granger Causality (GC), which provided a new neuromarker for stress classification. These features are combined with attention fusion, which enhances the discriminant features and mitigates the individual limitations within each modality. We also extracted microstates for stress-based signals. It provided a new set of microstate topomaps to study brain networks when under stress, which was not explored previously. The proposed Attention-fusion based multi-feature set is classified using Support Vector Machine, Linear Discriminant Analysis (LDA) and Multilayer Perceptron (MLP) and gave a reliable accuracy of 95.47%, 98.91%, and 83.49%, respectively. To validate the proposed method, the classification results were compared with individual and binary fusion of MS, TE and GC features, which further confirmed the robustness of the framework. This proposed feature fusion provides a more robust stress classification neuromarker, which can effectively cover the brain dynamics for accurate reporting of the underlying mental state.

Attention-based multi-feature fusion neuromarker for EEG-driven stress classification in learners.

A Comparison of the Clinical Characteristics of Short-, Mid-, and Long-Term Mortality in Patients Attended by the Emergency Medical Services: An Observational Study.

A Comprehensive Review of Recent Advances in Artificial Intelligence for Dentistry E-Health.

An Effective Method for Lung Cancer Diagnosis from CT Scan Using Deep Learning-Based Support Vector Network.

A Hybrid Temporal-spectral Load Forecasting Model with Static Context Fusion for Smart Cities.

An Integrated Machine Learning and Genomic Framework for Precise Detection of Gastric Cancer.

A Systematic Survey of AI Models in Financial Market Forecasting for Profitability Analysis.

A deep learning approach for Named Entity Recognition in Urdu language.

A lightweight deep learning approach for COVID-19 detection using X-ray images with edge federation.

A novel approach for disease and pests detection in potato production system based on deep learning.

Behavioral and Performance Analysis of a Real-Time Case Study Event Log: A Process Mining Approach.

Histopathological evaluation is necessary for the diagnosis and grading of prostate cancer, which is still one of the most common cancers in men globally. Traditional evaluation is time-consuming, prone to inter-observer variability, and challenging to scale. The clinical usefulness of current AI systems is limited by the need for comprehensive pixel-level annotations. The objective of this research is to develop and evaluate a large-scale benchmarking study on a weakly supervised deep learning framework that minimizes the need for annotation and ensures interpretability for automated prostate cancer diagnosis and International Society of Urological Pathology (ISUP) grading using whole slide images (WSIs). This study rigorously tested six cutting-edge multiple instance learning (MIL) architectures (CLAM-MB, CLAM-SB, ILRA-MIL, AC-MIL, AMD-MIL, WiKG-MIL), three feature encoders (ResNet50, CTransPath, UNI2), and four patch extraction techniques (varying sizes and overlap) using the PANDA dataset (10,616 WSIs), yielding 72 experimental configurations. The methodology used distributed cloud computing to process over 31 million tissue patches, implementing advanced attention mechanisms to ensure clinical interpretability through Grad-CAM visualizations. The optimum configuration (UNI2 encoder with ILRA-MIL, 256 256 patches, 50% overlap) achieved 78.75% accuracy and 90.12% quadratic weighted kappa (QWK), outperforming traditional methods and approaching expert pathologist-level diagnostic capability. Overlapping smaller patches offered the best balance of spatial resolution and contextual information, while domain-specific foundation models performed noticeably better than generic encoders. This work is the first large-scale, comprehensive comparison of weekly supervised MIL methods for prostate cancer diagnosis and grading. The proposed approach has excellent clinical diagnostic performance, scalability, practical feasibility through cloud computing, and interpretability using visualization tools.

Benchmarking multiple instance learning architectures from patches to pathology for prostate cancer detection and grading using attention-based weak supervision.

Breast Cancer Prediction Using Fine Needle Aspiration Features and Upsampling with Supervised Machine Learning.

Introduction: Jackfruit cultivation is highly affected by leaf diseases that reduce yield, fruit quality, and farmer income. Early diagnosis remains challenging due to the limitations of manual inspection and the lack of automated and scalable disease detection systems. Existing deep-learning approaches often suffer from limited generalization and high computational cost, restricting real-time field deployment. Methods: This study proposes CNNAttLSTM, a hybrid deep-learning architecture integrating Convolutional Neural Networks (CNN), Long Short-Term Memory (LSTM) units, and an attention mechanism for multi-class classification of algal leaf spot, black spot, and healthy jackfruit leaves. Each image is divided into ordered 56×56 spatial patches, treated as pseudo-temporal sequences to enable the LSTM to capture contextual dependencies across different leaf regions. Spatial features are extracted via Conv2D, MaxPooling, and GlobalAveragePooling layers; temporal modeling is performed by LSTM units; and an attention mechanism assigns adaptive weights to emphasize disease-relevant regions. Experiments were conducted on a publicly available Kaggle dataset comprising 38,019 images, using predefined training, validation, and testing splits. Results: The proposed CNNAttLSTM model achieved 99% classification accuracy, outperforming the baseline CNN (86%) and CNN–LSTM (98%) models. It required only 3.7 million parameters, trained in 45 minutes on an NVIDIA Tesla T4 GPU, and achieved an inference time of 22 milliseconds per image, demonstrating high computational efficiency. The patch-based pseudo-temporal approach improved spatial–temporal feature representation, enabling the model to distinguish subtle differences between visually similar disease classes. Discussion: Results show that combining spatial feature extraction with temporal modeling and attention significantly enhances robustness and classification performance in plant disease detection. The lightweight design enables real-time and edge-device deployment, addressing a major limitation of existing deep-learning techniques. The findings highlight the potential of CNNAttLSTM for scalable, efficient, and accurate agricultural disease monitoring and broader precision agriculture applications.

CNNAttLSTM: an attention-enhanced CNN–LSTM architecture for high-precision jackfruit leaf disease classification.

Chronotype and Cancer: Emerging Relation Between Chrononutrition and Oncology from Human Studies.

Clinical phenotypes and short-term outcomes based on prehospital point-of-care testing and on-scene vital signs.

Competitive Coevolution-Based Improved Phasor Particle Swarm Optimization Algorithm for Solving Continuous Problems.

Consumption of ultra-processed foods is associated with cognitive status in elderly patients.

Contextual Urdu Lemmatization Using Recurrent Neural Network Models.

Correction: Enhancing fault detection in new energy vehicles via novel ensemble approach.

Deep Learning-Based Multiclass Instance Segmentation for Dental Lesion Detection.

Deep Learning-Based Real Time Defect Detection for Optimization of Aircraft Manufacturing and Control Performance.

Deep image features sensing with multilevel fusion for complex convolution neural networks & cross domain benchmarks.

Predicting depression intensity from microblogs and social media posts has numerous benefits and applications, including predicting early psychological disorders and stress in individuals or the general public. A major challenge in predicting depression using social media posts is that the existing studies do not focus on predicting the intensity of depression in social media texts but rather only perform the binary classification of depression and moreover noisy data makes it difficult to predict the true depression in the social media text. This study intends to begin by collecting relevant Tweets and generating a corpus of 210000 public tweets using Twitter public application programming interfaces (APIs). A strategy is devised to filter out only depression-related tweets by creating a list of relevant hashtags to reduce noise in the corpus. Furthermore, an algorithm is developed to annotate the data into three depression classes: ‘Mild,’ ‘Moderate,’ and ‘Severe,’ based on International Classification of Diseases-10 (ICD-10) depression diagnostic criteria. Different baseline classifiers are applied to the annotated dataset to get a preliminary idea of classification performance on the corpus. Further FastText-based model is applied and fine-tuned with different preprocessing techniques and hyperparameter tuning to produce the tuned model, which significantly increases the depression classification performance to an 84% F1 score and 90% accuracy compared to baselines. Finally, a FastText-based weighted soft voting ensemble (WSVE) is proposed to boost the model’s performance by combining several other classifiers and assigning weights to individual models according to their individual performances. The proposed WSVE outperformed all baselines as well as FastText alone, with an F1 of 89%, 5% higher than FastText alone, and an accuracy of 93%, 3% higher than FastText alone. The proposed model better captures the contextual features of the relatively small sample class and aids in the detection of early depression intensity prediction from tweets with impactful performances.

Depression Intensity Classification from Tweets Using FastText Based Weighted Soft Voting Ensemble.

Patient care and convenience remain the concern of medical professionals and caregivers alike. An unconscious patient confined to a bed may develop fluid accumulation and pressure sores due to inactivity and deficiency of oxygen flow. Moreover, weight monitoring is crucial for an effective treatment plan, which is difficult to measure for bedridden patients. This paper presents the design and development of a smart and cost-effective independent system for lateral rotation, movement, weight measurement, and transporting immobile patients. Optimal dimensions and practical design specifications are determined by a survey across various hospitals. Subsequently, the proposed hoist-based weighing and turning mechanism is CAD-modeled and simulated. Later, the structural analysis is carried out to select suitable metallurgy for various sub-assemblies to ensure design reliability. After fabrication, optimization, integration, and testing procedures, the base frame is designed to mount a hydraulic motor for the actuator, a DC power source for self-sustenance, and lockable wheels for portability. The installation of a weighing scale and a hydraulic actuator is ensured to lift the patient for weight measuring up to 600 pounds or lateral turning of 80 degrees both ways. The developed system offers simple operating characteristics, allows for keeping patient weight records, and assists nurses in changing patients’ lateral positions both ways, comfortably massage patients’ backs, and transport them from one bed to another. Additionally, being lightweight offers reduced contact with the patient to increase the healthcare staff’s safety in pandemics; it is also height adjustable and portable, allowing for use with multiple-sized beds and easy transportation across the medical facility. The feedback from paramedics is encouraging regarding reducing labor-intensive nursing tasks, alleviating the discomfort of long-term bed-ridden patients, and allowing medical practitioners to suggest better treatment plans

Design and Development of Smart Weight Measurement, Lateral Turning and Transfer Bedding for Unconscious Patients in Pandemics.

Design and development of patient health tracking, monitoring and big data storage using Internet of Things and real time cloud computing.

Detecting Pragmatic Ambiguity in Requirement Specification Using Novel Concept Maximum Matching Approach Based on Graph Network.

Detecting hate in diversity: a survey of multilingual code-mixed image and video analysis.

Development Agencies and Local Governments—Coexistence within the Same Territory.

DrunkChain: Blockchain-Based IoT System for Preventing Drunk Driving-Related Traffic Accidents.

Mango is one of the most beloved fruits and plays an indispensable role in the agricultural economies of many tropical countries like Pakistan, India, and other Southeast Asian countries. Similar to other fruits, mango cultivation is also threatened by various diseases, including Anthracnose and Red Rust. Although farmers try to mitigate such situations on time, early and accurate detection of mango diseases remains challenging due to multiple factors, such as limited understanding of disease diversity, similarity in symptoms, and frequent misclassification. To avoid such instances, this study proposes a multimodal deep learning framework that leverages both leaf and fruit images to improve classification performance and generalization. Individual CNN-based pre-trained models, including ResNet-50, MobileNetV2, EfficientNet-B0, and ConvNeXt, were trained separately on curated datasets of mango leaf and fruit diseases. A novel Modality Attention Fusion (MAF) mechanism was introduced to dynamically weight and combine predictions from both modalities based on their discriminative strength, as some diseases are more prominent on leaves than on fruits, and vice versa. To address overfitting and improve generalization, a class-aware augmentation pipeline was integrated, which performs augmentation according to the specific characteristics of each class. The proposed attention-based fusion strategy significantly outperformed individual models and static fusion approaches, achieving a test accuracy of 99.08%, an F1 score of 99.03%, and a perfect ROC-AUC of 99.96% using EfficientNet-B0 as the base. To evaluate the model’s real-world applicability, an interactive web application was developed using the Django framework and evaluated through out-of-distribution (OOD) testing on diverse mango samples collected from public sources. These findings underline the importance of combining visual cues from multiple organs of plants and adapting model attention to contextual features for real-world agricultural diagnostics.

Dual-modality fusion for mango disease classification using dynamic attention based ensemble of leaf & fruit images.

Edge-Based Autonomous Fire and Smoke Detection Using MobileNetV2.

Efficient CNN architecture with image sensing and algorithmic channeling for dataset harmonization.

Emotion Detection Using Facial Expression Involving Occlusions and Tilt.

Emotional Management in Journalism and Communication Studies.

Enhanced interpretable thyroid disease diagnosis by leveraging synthetic oversampling and machine learning models.

Introduction: Weather classification plays a crucial role in applications such as environmental monitoring, disaster management, and smart city infrastructure. Accurate and efficient classification of weather conditions from images remains a challenging task due to variations in illumination, texture, and atmospheric conditions.Methods: This study proposes an efficient deep learning framework for multi-class weather classification by integrating the Xception architecture with Squeeze-and-Excitation (SE) blocks and a spatial attention mechanism. Transfer learning with pre-trained ImageNet weights was employed, and a comparative analysis was conducted using EfficientNet-B3, ResNet152V2, and Xception architectures. The proposed enhanced Xception model incorporates channel-wise recalibration and spatial feature refinement to improve representational capability. The model was trained and evaluated on the Multi-Class Weather Dataset (MWD), which consists of 1,125 images categorized into four classes: sunshine, cloudy, rain, and sunrise. To ensure robustness and generalization, 5-fold cross-validation, statistical significance testing, calibration analysis, and robustness evaluation under image perturbations were performed.Results: The proposed model achieved a classification accuracy of 99.06% on the test set. Additionally, it attained a macro precision of 98.3%, macro recall of 97.7%, and macro F1-score of 98.0%. The model demonstrated strong generalization capability and robustness under varying perturbation conditions, with only moderate computational overhead.Discussion: The integration of SE blocks and spatial attention significantly enhances feature representation by emphasizing informative channels and spatial regions. Compared to baseline architectures, the proposed framework shows superior performance in terms of accuracy and robustness. These results indicate that the model is well-suited for real-world weather classification applications, particularly in intelligent environmental monitoring systems.

Enhanced weather classification using xception with SENet and attention mechanisms.

Enhancing Cricket Performance Analysis with Human Pose Estimation and Machine Learning.

Enhancing fault detection in new energy vehicles via novel ensemble approach.

Ensemble Partition Sampling (EPS) for Improved Multi-Class Classification.

Ensemble stacked model for enhanced identification of sentiments from IMDB reviews.

Environmental burden of fish in healthy and sustainable diets.

Evaluation of the Sustainable Development Goals in the Diagnosis and Prediction of the Sustainability of Projects Aimed at Local Communities in Latin America and the Caribbean.

Evolving epidemiology, clinical features, and genotyping of dengue outbreaks in Bangladesh, 2000–2024: a systematic review.

FMDNet: An Efficient System for Face Mask Detection Based on Lightweight Model during COVID-19 Pandemic in Public Areas.

Background Age-related structural changes in the human brain, including cortical atrophy, reductions in grey and white matter volumes, and the accumulation of small vessel–related lesions such as white matter hyperintensities (WMH) and cerebral microbleeds, represent critical biological substrates underlying cognitive decline and dementia. Fish consumption has been associated with slower cognitive decline and reduced risk of dementia, but a comprehensive evaluation of its relation with brain structures is lacking. Aims The aim of this study was to systematically review current scientific literature providing evidence of relation between fish intake and brain structures in human studies. Methods Studies indexed in two major electronic databases have been screened based on a combination of keywords and MeSH terms. Studies were eligible whether they assessed fish consumption in relation to brain structures in the adult populations. Results A total of 24 studies conducted predominantly on older adults met inclusion criteria. Most brain volume measures were obtained via magnetic resonance imaging (MRI) procedures. Higher fish consumption was associated with reduced severity of white matter hyperintensities (a biomarker of cerebral small vessel disease and white matter damage) and cerebral micro-bleed, preservation of certain brain areas volumes (i.e., hippocampus, temporal lobe and periventricle white matter) and cortical thickness of specific areas (i.e., precuneus, parietal, and cingulate grey matter), among others, compared to lower intake. Some analyses found no association and isolated findings suggested possible adverse associations that were not consistently replicated. Studies reporting null findings may underline the possible relevance of the overall diet (i.e., adherence to the Mediterranean diet). Conclusions Inclusion of fish in a healthy and balanced diet is associated with better white matter grades on MRI and slower progression of white matter hyperintensities and reduction of vascular-related lesions of the aging brain, suggesting a potential role in preventing neurocognitive deterioration. Heterogeneity across studies underscores the need for additional studies.

Fish consumption and brain structure: a comprehensive systematic review of observational studies.

Formal modeling and analysis of security schemes of RPL protocol using colored Petri nets.

Fundus image classification using feature concatenation for early diagnosis of retinal disease.

Human activity recognition (HAR) is essential in many applications, such as smart homes, assisted living, healthcare monitoring, rehabilitation, physiotherapy, and geriatric care. Conventional methods of HAR use wearable sensors, e.g., acceleration sensors and gyroscopes. However, they are limited by issues such as sensitivity to position, user inconvenience, and potential health risks with long-term use. Optical camera systems that are vision-based provide an alternative that is not intrusive; however, they are susceptible to variations in lighting, intrusions, and privacy issues. The paper uses an optical method of recognizing human domestic activities based on pose estimation and deep learning ensemble models. The skeletal keypoint features proposed in the current methodology are extracted from video data using PoseNet to generate a privacy-preserving representation that captures key motion dynamics without being sensitive to changes in appearance. A total of 30 subjects (15 male and 15 female) were sampled across 2734 activity samples, including nine daily domestic activities. There were six deep learning architectures, namely, the Transformer (Transformer), Long Short-Term Memory (LSTM), Gated Recurrent Unit (GRU), Multilayer Perceptron (MLP), One-Dimensional Convolutional Neural Network (1D CNN), and a hybrid Convolutional Neural Network–Long Short-Term Memory (CNN–LSTM) architecture. The results on the hold-out test set show that the CNN–LSTM architecture achieves an accuracy of 98.78% within our experimental setting. Leave-One-Subject-Out cross-validation further confirms robust generalization across unseen individuals, with CNN–LSTM achieving a mean accuracy of 97.21% ± 1.84% across 30 subjects. The results demonstrate that vision-based pose estimation with deep learning is a useful, precise, and non-intrusive approach to HAR in smart healthcare and home automation systems.

Human Activity Recognition in Domestic Settings Based on Optical Techniques and Ensemble Models.

Human‐based new approach methodologies to accelerate advances in nutrition research.

Image Watermarking Using Least Significant Bit and Canny Edge Detection.

Impact of Innovation-Oriented Human Resource on Small and Medium Enterprises’ Performance.

Angola, as with many countries on the African continent, has great inequalities or asymmetries between its provinces. At the economic, financial, and technological level, there is a great disparity between them, where it is observed that the province of Luanda is the largest financial business center to the detriment of others, such as Moxico, Zaire, and Cabinda. In the latter, despite the advantages of high oil production, from a regional point of view, they remain almost stagnant in time, in a social dysfunction where the population lives on extractivism and artisanal fishing. This article analyzes the most important events in contemporary regional history, the Portuguese occupation that was the Portuguese colonial rule over Angola (1890–1930) and the civil war that was a struggle between Angolans for control of the country (1975–2002), in the consolidation of the asymmetries between provinces. For this work, a theoretical-reflective study was conducted based on the reading of books, articles, and previous investigations on the phenomenon studied. Considering the interpretation and analysis of the theoretical content obtained through the bibliographic research conducted, this theoretical construction approaches the qualitative approach. We conclude that the deep inequalities between regions and within them, between the provinces studied, originated historically in the form of exploitation of the regions and from the consequences of the war. The asymmetries, observed through the variables studied show that the provinces historically explored and considered object regions present a lower growth compared to those that were considered subject regions in which the applied geopolitical strategy, as they are centers of primary production flows, was different. We also observe that, due to the conflicts of the civil war in the less developed regions, the inequalities have deepened, contributing seriously to a higher level of poverty and a lower development of the provinces where these conflicts took place.

Inequalities and Asymmetries in the Development of Angola’s Provinces: The Impact of Colonialism and Civil War.

Infrared thermography to assess fatigue, injury risk factors and recovery in soccer: a systematic review of original studies.

Integration of Sustainable Criteria in the Development of a Proposal for an Online Postgraduate Program in the Projects Area.

IoT Enabled Intelligent Stick for Visually Impaired People for Obstacle Recognition.

IoTTPS: Ensemble RKSVM Model-Based Internet of Things Threat Protection System.

Molecular epidemiology, transmission and clinical features of 2022‐mpox outbreak: A systematic review.

Multipath Routing in Wireless Body Area Sensor Network for Healthcare Monitoring.

Novel Transfer Learning Approach for Detecting Infected and Healthy Maize Crop Using Leaf Images.

Novel model to authenticate role-based medical users for blockchain-based IoMT devices.

Organizational Culture Assessment Based on a Values-Based Coaching Program for Strategic Level Employees: The Case of GEDEME, Cuba.

PRUS: Product Recommender System Based on User Specifications and Customers Reviews.

Performance of the 4C and SEIMC scoring systems in predicting mortality from onset to current COVID-19 pandemic in emergency departments.

Pneumonia Detection Using Chest Radiographs With Novel EfficientNetV2L Model.

Prediction β-Thalassemia carriers using complete blood count features.

Prehospital acute life-threatening cardiovascular disease in elderly: an observational, prospective, multicentre, ambulance-based cohort study.

Prehospital qSOFA, mSOFA, and NEWS2 performance for sepsis prediction: A prospective, multi-center, cohort study.

Prevalence and impact of long COVID-19 among patients with diabetes and cardiovascular diseases in Bangladesh.

Prickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean diet.

Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation.

Quantifying Domain-Specific Risk Signals in Lung Cancer Severity Prediction: A Multi-Domain Ablation Study Using XGBoost and SHAP.

Railway Track Fault Detection Using Selective MFCC Features from Acoustic Data.

Real Word Spelling Error Detection and Correction for Urdu Language.

Cardiovascular diseases are among the leading causes of mortality worldwide, with dietary factors being the main risk contributors. Diets rich in bioactive compounds, such as (poly)phenols, have been shown to potentially exert positive effects on vascular health. Among them, resveratrol has gained particular attention due to its potential antioxidant and anti-inflammatory action. Nevertheless, the results in humans are conflicting possibly due to interindividual different responses. The gut microbiota, a complex microbial community that inhabits the gastrointestinal tract, has been called out as potentially responsible for modulating the biological activities of phenolic metabolites in humans. The present review aims to summarize the main findings from clinical trials on the effects of resveratrol interventions on endothelial and vascular outcomes and review potential mechanisms interesting the role of gut microbiota on the metabolism of this molecule and its cardioprotective metabolites. The findings from randomized controlled trials show contrasting results on the effects of resveratrol supplementation and vascular biomarkers without dose-dependent effect. In particular, studies in which resveratrol was integrated using food sources, i.e., red wine, reported significant effects although the resveratrol content was, on average, much lower compared to tablet supplementation, while other studies with often extreme resveratrol supplementation resulted in null findings. The results from experimental studies suggest that resveratrol exerts cardioprotective effects through the modulation of various antioxidant, anti-inflammatory, and anti-hypertensive pathways, and microbiota composition. Recent studies on resveratrol-derived metabolites, such as piceatannol, have demonstrated its effects on biomarkers of vascular health. Moreover, resveratrol itself has been shown to improve the gut microbiota composition toward an anti-inflammatory profile. Considering the contrasting findings from clinical studies, future research exploring the bidirectional link between resveratrol metabolism and gut microbiota as well as the mediating effect of gut microbiota in resveratrol effect on cardiovascular health is warranted.