Documentos donde el Tema es "Materias > Alimentación"

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Número de registros en este nivel: 7.

2024

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Abierto Inglés Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research. metadata Cassotta, Manuela; Cianciosi, Danila; Elexpuru Zabaleta, Maria; Elío Pascual, Iñaki; Sumalla Cano, Sandra; Giampieri, Francesca y Battino, Maurizio mail manucassotta@gmail.com, SIN ESPECIFICAR, maria.elexpuru@uneatlantico.es, inaki.elio@uneatlantico.es, sandra.sumalla@uneatlantico.es, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es (2024) Human‐based new approach methodologies to accelerate advances in nutrition research. Food Frontiers. pp. 1-32. ISSN 2643-8429

2023

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Diets enriched in plant-based foods are associated with the maintenance of a good well-being and with the prevention of many non-communicable diseases. The health effects of fruits and vegetables consumption are mainly due to the presence of micronutrients, including vitamins and minerals, and polyphenols, plant secondary metabolites. One of the most important classes of phenolic compounds are anthocyanins, that confer the typical purple-red color to many foods, such as berries, peaches, plums, red onions, purple corn, eggplants, as well as purple carrots, sweet potatoes and red cabbages, among others. This commentary aims to briefly highlight the progress made by science in the last years, focusing on some unexpected aspects related with anthocyanins, such as their bioavailability, their health effects and their relationship with gut microbiota metadata Giampieri, Francesca; Cianciosi, Danila; Alvarez-Suarez, José M.; Quiles, José L.; Forbes-Hernández, Tamara Y.; Navarro-Hortal, María D.; Machì, Michele; Pali-Casanova, Ramón; Martínez Espinosa, Julio César; Chen, Xiumin; Zhang, Di; Bai, Weibin; Lingmin, Tian; Mezzetti, Bruno; Battino, Maurizio y Diaz, Yasmany Armas mail francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, jose.quiles@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, ramon.pali@unini.edu.mx, ulio.martinez@unini.edu.mx, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR (2023) Anthocyanins: what do we know until now? Journal of Berry Research. pp. 1-6. ISSN 18785093

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Betalains are water-soluble, nitrogen-containing vacuolar pigment and can be divided into two subclasses: the yellow – orange betaxanthins and the red – violet betacyanin. These pigments can be found mainly in Latin America, but also in some parts of Asia, Africa, Australia and in the Mediterranean area. In this work an overview related with the status of research about betalains extracted from Opuntia spp and the enforces made to evaluate their positive incidence in the human body is provided. Several studies enhance their anticancer, anti-inflammatory and antioxidant properties. They also exhibit antimicrobial and antidiabetic effect. Taking into account these properties, betalains seem to be a promising natural alternative as a colorant to replace the synthetic ones in the food additive industry. In addition, the use of Opuntia spp fruits as possible colorant sources in the Food Industry, may contribute positively to the sustainable development in semi-arid regions. metadata Armas Diaz, Yasmany; Qi, Zexiu; Yang, Bei; Martínez López, Nohora Milena; Briones Urbano, Mercedes y Cianciosi, Danila mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, SIN ESPECIFICAR (2023) Betalains: The main bioactive compounds of Opuntia spp and their possible health benefits in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 16 (3). pp. 181-190. ISSN 1973798X

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Abierto Inglés Alpha-linolenic acid (ALA) is a long-chain polyunsaturated essential fatty acid of the Ω3 series found mainly in vegetables, especially in the fatty part of oilseeds, dried fruit, berries, and legumes. It is very popular for its preventive use in several diseases: It seems to reduce the risk of the onset or decrease some phenomena related to inflammation, oxidative stress, and conditions of dysregulation of the immune response. Recent studies have confirmed these unhealthy situations also in patients with severe coronavirus disease 2019 (COVID-19). Different findings (in vitro, in vivo, and clinical ones), summarized and analyzed in this review, have showed an important role of ALA in other various non-COVID physiological and pathological situations against “cytokines storm,” chemokines secretion, oxidative stress, and dysregulation of immune cells that are also involved in the infection of the 2019 novel coronavirus. According to the effects of ALA against all the aforementioned situations (also present in patients with a severe clinical picture of severe acute respiratory syndrome-(CoV-2) infection), there may be the biologic plausibility of a prophylactic effect of this compound against COVID-19 symptoms and fatality. metadata Cianciosi, Danila; Diaz, Yasmany Armas; Gaddi, Antonio Vittorino; Capello, Fabio; Savo, Maria Teresa; Pali-Casanova, Ramón; Martínez Espinosa, Julio César; Pascual Barrera, Alina Eugenia; Navarro‐Hortal, Maria‐Dolores; Tian, Lingmin; Bai, Weibin; Giampieri, Francesca y Battino, Maurizio mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, ramon.pali@unini.edu.mx, ulio.martinez@unini.edu.mx, alina.pascual@unini.edu.mx, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR (2023) Can alpha‐linolenic acid be a modulator of “cytokine storm,” oxidative stress and immune response in SARS‐CoV‐2 infection? Food Frontiers. ISSN 2643-8429

Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Cerrado Inglés Manuka honey, which is rich in pinocembrin, quercetin, naringenin, salicylic, p-coumaric, ferulic, syringic and 3,4-dihydroxybenzoic acids, has been shown to have pleiotropic effects against colon cancer cells. In this study, potential chemosensitizing effects of Manuka honey against 5-Fluorouracil were investigated in colonspheres enriched with cancer stem cells (CSCs), which are responsible for chemoresistance. Results showed that 5-Fluorouracil increased when it was combined with Manuka honey by downregulating the gene expression of both ATP-binding cassette sub-family G member 2, an efflux pump and thymidylate synthase, the main target of 5-Fluorouracil which regulates the ex novo DNA synthesis. Manuka honey was associated with decreased self-renewal ability by CSCs, regulating expression of several genes in Wnt/β-catenin, Hedgehog and Notch pathways. This preliminary study opens new areas of research into the effects of natural compounds in combination with pharmaceuticals and, potentially, increase efficacy or reduce adverse effects. metadata Cianciosi, Danila; Armas Diaz, Yasmany; Alvarez-Suarez, José M.; Chen, Xiumin; Zhang, Di; Martínez López, Nohora Milena; Briones Urbano, Mercedes; Quiles, José L.; Amici, Adolfo; Battino, Maurizio y Giampieri, Francesca mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, jose.quiles@uneatlantico.es, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es (2023) Can the phenolic compounds of Manuka honey chemosensitize colon cancer stem cells? A deep insight into the effect on chemoresistance and self-renewal. Food Chemistry, 427. p. 136684. ISSN 03088146

2022

Revista Materias > Alimentación Universidad Europea del Atlántico > Investigación > Revistas Científicas
Universidad Internacional Iberoamericana México > Investigación > Revistas Científicas
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Revistas Científicas
Universidad Internacional do Cuanza > Investigación > Revistas Científicas
Fundación Universitaria Internacional de Colombia > Investigación > Revistas Científicas
Abierto Inglés La revista MLS Health and Nutrition Research nace como una publicación semestral con el objetivo de publicar artículos originales de investigación y de revisión tanto en áreas básicas como aplicadas y metodológicas que supongan una contribución científica al progreso de cualquier ámbito de la salud y nutrición como objetivo principal. Los artículos incluidos en esta revista se publican en español, portugués e inglés. La vocación internacional de esta revista promueve la difusión del conocimiento en sus diferentes áreas. metadata SIN ESPECIFICAR mail mls@devnull.funiber.org (2022) MLS Health and Nutrition Research. [Revista]

Artículo Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Producción Científica
Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica
Universidad Internacional Iberoamericana México > Investigación > Producción Científica
Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica
Universidad Internacional do Cuanza > Investigación > Producción Científica
Cerrado Inglés Cactus has been used in traditional folk medicine because of its role in treating a number of diseases and conditions. Prickly pear fruit is an excellent source of secondary metabolites (i.e., betalains, flavonoids, and ascorbic acid) with health-promoting properties against many common human diseases, including diabetes, hypertension, hypercholesterolemia, rheumatic pain, gastric mucosa diseases and asthma. In addition, prickly pears are potential candidates for the development of low-cost functional foods because they grow with low water requirements in arid regions of the world. This review describes the main bioactive compounds found in this fruit and shows the in vitro and some clinical studies about the fruit of most important cactus (Opuntia ficus-indica) and its relationship with some chronic diseases. Even though a lot of effort have been done to study the relationship between this fruit and the human health, more studies on Opuntia ficus-indica could help better understand its pharmacological mechanism of action to provide clear scientific evidence to explain its traditional uses, and to identify its therapeutic potential in other diseases. metadata Armas Diaz, Yasmany; Machì, Michele; Salinari, Alessia; Mazas Pérez-Oleaga, Cristina; Martínez López, Nohora Milena; Briones Urbano, Mercedes y Cianciosi, Danila mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, cristina.mazas@uneatlantico.es, nohora.martinez@uneatlantico.es, mercedes.briones@uneatlantico.es, SIN ESPECIFICAR (2022) Prickly pear fruits from "Opuntia ficus-indica" varieties as a source of potential bioactive compounds in the Mediterranean diet. Mediterranean Journal of Nutrition and Metabolism, 15 (4). pp. 581-592. ISSN 1973798X

Este listado fue generado el Wed Mar 27 23:41:45 2024 UTC.

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Human‐based new approach methodologies to accelerate advances in nutrition research

Much of nutrition research has been conventionally based on the use of simplistic in vitro systems or animal models, which have been extensively employed in an effort to better understand the relationships between diet and complex diseases as well as to evaluate food safety. Although these models have undeniably contributed to increase our mechanistic understanding of basic biological processes, they do not adequately model complex human physiopathological phenomena, creating concerns about the translatability to humans. During the last decade, extraordinary advancement in stem cell culturing, three-dimensional cell cultures, sequencing technologies, and computer science has occurred, which has originated a wealth of novel human-based and more physiologically relevant tools. These tools, also known as “new approach methodologies,” which comprise patient-derived organoids, organs-on-chip, multi-omics approach, along with computational models and analysis, represent innovative and exciting tools to forward nutrition research from a human-biology-oriented perspective. After considering some shortcomings of conventional in vitro and vivo approaches, here we describe the main novel available and emerging tools that are appropriate for designing a more human-relevant nutrition research. Our aim is to encourage discussion on the opportunity to explore innovative paths in nutrition research and to promote a paradigm-change toward a more human biology-focused approach to better understand human nutritional pathophysiology, to evaluate novel food products, and to develop more effective targeted preventive or therapeutic strategies while helping in reducing the number and replacing animals employed in nutrition research.

Producción Científica

Manuela Cassotta mail manucassotta@gmail.com, Danila Cianciosi mail , Maria Elexpuru Zabaleta mail maria.elexpuru@uneatlantico.es, Iñaki Elío Pascual mail inaki.elio@uneatlantico.es, Sandra Sumalla Cano mail sandra.sumalla@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es,

Cassotta

<a href="/11322/1/journal.pone.0298582.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/style/images/fileicons/text.png" border="0"/></a>

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Design and development of patient health tracking, monitoring and big data storage using Internet of Things and real time cloud computing

With the outbreak of the COVID-19 pandemic, social isolation and quarantine have become commonplace across the world. IoT health monitoring solutions eliminate the need for regular doctor visits and interactions among patients and medical personnel. Many patients in wards or intensive care units require continuous monitoring of their health. Continuous patient monitoring is a hectic practice in hospitals with limited staff; in a pandemic situation like COVID-19, it becomes much more difficult practice when hospitals are working at full capacity and there is still a risk of medical workers being infected. In this study, we propose an Internet of Things (IoT)-based patient health monitoring system that collects real-time data on important health indicators such as pulse rate, blood oxygen saturation, and body temperature but can be expanded to include more parameters. Our system is comprised of a hardware component that collects and transmits data from sensors to a cloud-based storage system, where it can be accessed and analyzed by healthcare specialists. The ESP-32 microcontroller interfaces with the multiple sensors and wirelessly transmits the collected data to the cloud storage system. A pulse oximeter is utilized in our system to measure blood oxygen saturation and body temperature, as well as a heart rate monitor to measure pulse rate. A web-based interface is also implemented, allowing healthcare practitioners to access and visualize the collected data in real-time, making remote patient monitoring easier. Overall, our IoT-based patient health monitoring system represents a significant advancement in remote patient monitoring, allowing healthcare practitioners to access real-time data on important health metrics and detect potential health issues before they escalate.

Producción Científica

Md. Milon Islam mail , Imran Shafi mail , Sadia Din mail , Siddique Farooq mail , Isabel de la Torre Díez mail , Jose Breñosa mail josemanuel.brenosa@uneatlantico.es, Julio César Martínez Espinosa mail ulio.martinez@unini.edu.mx, Imran Ashraf mail ,

Islam

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Detecting Pragmatic Ambiguity in Requirement Specification Using Novel Concept Maximum Matching Approach Based on Graph Network

Requirements specifications written in natural language enable us to understand a program’s intended functionality, which we can then translate into operational software. At varying stages of requirement specification, multiple ambiguities emerge. Ambiguities may appear at several levels including the syntactic, semantic, domain, lexical, and pragmatic levels. The primary objective of this study is to identify requirements’ pragmatic ambiguity. Pragmatic ambiguity occurs when the same set of circumstances can be interpreted in multiple ways. It requires consideration of the context statement of the requirements. Prior research has developed methods for obtaining concepts based on individual nodes, so there is room for improvement in the requirements interpretation procedure. This research aims to develop a more effective model for identifying pragmatic ambiguity in requirement definition. To better interpret requirements, we introduced the Concept Maximum Matching (CMM) technique, which extracts concepts based on edges. The CMM technique significantly improves precision because it permits a more accurate interpretation of requirements based on the relative weight of their edges. Obtaining an F-measure score of 0.754 as opposed to 0.563 in existing models, the evaluation results demonstrate that CMM is a substantial improvement over the previous method.

Producción Científica

Khadija Aslam mail , Faiza Iqbal mail , Ayesha Altaf mail , Naveed Hussain mail , Mónica Gracia Villar mail monica.gracia@uneatlantico.es, Emmanuel Soriano Flores mail emmanuel.soriano@uneatlantico.es, Isabel De La Torre Diez mail , Imran Ashraf mail ,

Aslam

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Depression Intensity Classification from Tweets Using FastText Based Weighted Soft Voting Ensemble

Predicting depression intensity from microblogs and social media posts has numerous benefits and applications, including predicting early psychological disorders and stress in individuals or the general public. A major challenge in predicting depression using social media posts is that the existing studies do not focus on predicting the intensity of depression in social media texts but rather only perform the binary classification of depression and moreover noisy data makes it difficult to predict the true depression in the social media text. This study intends to begin by collecting relevant Tweets and generating a corpus of 210000 public tweets using Twitter public application programming interfaces (APIs). A strategy is devised to filter out only depression-related tweets by creating a list of relevant hashtags to reduce noise in the corpus. Furthermore, an algorithm is developed to annotate the data into three depression classes: ‘Mild,’ ‘Moderate,’ and ‘Severe,’ based on International Classification of Diseases-10 (ICD-10) depression diagnostic criteria. Different baseline classifiers are applied to the annotated dataset to get a preliminary idea of classification performance on the corpus. Further FastText-based model is applied and fine-tuned with different preprocessing techniques and hyperparameter tuning to produce the tuned model, which significantly increases the depression classification performance to an 84% F1 score and 90% accuracy compared to baselines. Finally, a FastText-based weighted soft voting ensemble (WSVE) is proposed to boost the model’s performance by combining several other classifiers and assigning weights to individual models according to their individual performances. The proposed WSVE outperformed all baselines as well as FastText alone, with an F1 of 89%, 5% higher than FastText alone, and an accuracy of 93%, 3% higher than FastText alone. The proposed model better captures the contextual features of the relatively small sample class and aids in the detection of early depression intensity prediction from tweets with impactful performances.

Producción Científica

Muhammad Rizwan mail , Muhammad Faheem Mushtaq mail , Maryam Rafiq mail , Arif Mehmood mail , Isabel de la Torre Diez mail , Mónica Gracia Villar mail monica.gracia@uneatlantico.es, Helena Garay mail helena.garay@uneatlantico.es, Imran Ashraf mail ,

Rizwan

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Diagnosing Training Needs in European Tourism SMEs: The TC-NAV Project for Managing and Overcoming Virulent Crises

This research aims to gather opinions from experts in the European tourism sector regarding training needs to address severe crises, such as Covid, in Small and Medium-Sized Enterprises (SMEs) across five countries: Spain, Iceland, Ireland, Scotland, and Germany. This study was conducted within the scope of the European TC-NAV project, which is funded by the European Union. The ultimate goal of this project is to develop training solutions for European SMEs Most existing literature on tourism crises primarily examines the impact on destinations as a whole rather than on individual tourism enterprises. Thus, this research is both relevant and timely The methodology employed was qualitative, and data being collected using a 9-question interview guide. This guide underwent validation by experts, achieving a Cronbach's Alpha value of 0.7. In total, 30 individuals were interviewed: 5 civil servants, 9 company directors, 5 university professors, 6 researchers, and 5 entrepreneurs. Some notable findings include the importance of innovation for change, promoting sustainable tourism, fostering informal partnerships among regional companies, the essential role of government support, the benefits of flexible planning and service digitisation, and the ongoing need for training and upskilling.

Producción Científica

Emmanuel Soriano Flores mail emmanuel.soriano@uneatlantico.es, Thomas Prola mail thomas.prola@uneatlantico.es, Íris Hrund Halldórsdóttir Halldórsdóttir mail , Steve Taylor mail ,

Soriano Flores